Stem Cell Regeneration
Astragulus Root Extract (Astragaloside IV) (Anti-inflammatory, Anti-Tumor, Anti-Microbial activity) that a simple preparations of this herb stimulate the immune system in several ways. It increases the number of stem cells in the small Intestines, and bone marrow, It stimulates the “germ-eating” white blood cells known as macrophages, activates T-cells and natural killer (NIK) cells. As an anti-tumor agent, astragalus prevented cancer metastasis in 80 percent of mice tested. Still other studies have shown that astragalus stimulated T-cell activity and restores immune function in cancer patients with impaired immune functions.
The action of astragalus is comprehensive. Robyn Landis and K. P. Khalsa note that “astragalus stimulates phagocytosis aggressiveness of their activity. Increased macrophage activity has been measured as lasting up to seventy-two hours. It increases the number of stem cells (the ‘generic’ cells that can become any type needed) in the marrow and lymph tissue, stimulates their maturation into active immune cells, increases spleen activity, increases releases of antibodies, and boost the production of hormonal messenger molecules that signal for virus destruction.” And as Rob McCaleb noted in HerbalGram 21 (summer 1988) researchers at the University of Texas Medical Center found that astragalus was able to completely restore the function of cancer patients’ compromised immune cells. (Note: the other herb which have shown simular results is Echinacea, more on that soon with a tincture and herbal tea formula…..)
The glyconutrients in the stem and branches of Astragalus are galactose, arabinose, xylose, fucose, rhamnose, and galcturonic acid. The benefits include action as an antioxidant, diuretic, anti-inflammatory. It inhibits tumour growth, offsets the immune suppression of cancer chemotherapy. Astragalus also stimulates synthesis of antibodies, delays the natural aging process of blastocysts (fertilised egg cells) by one third, increases the number of stem cells in marrow and lymph and stimulates stem cell development into active immune cells.
Astragalus is used for various health conditions. For instance, it’s used to treat the common cold, upper respiratory infections, firbromyalghia, diabetes and for its heart benefits. Astragalus stimulates the spleen, liver, lungs, circulatory, and urinary system. It’s also used to treat arthritis, asthma, and nervous conditions as well as to lower blood sugar and blood pressure
Research at the UCLA AIDS Institute focused on the function of cycloastragenol in the aging process of immune cells, and its effects on the cells’ response to viral infections. It appears to increase the production of telomerase, an enzyme that mediates the replacement of short bits of DNA known as telomeres, which play a key role in cell replication, including in cancer processes.
Immunopotentiating effects of four Chinese herbal polysaccharides administered at vaccination in chickens.
The results showed that astragalus polysaccharide and isatis root polysaccharide at low dosages, and achyranthes root polysaccharide and Chinese yam polysaccharide at high dosages significantly enhanced the ND antibody titers, concanavalin A-induced proliferation of peripheral blood lymphocytes, and ratio of CD4(+) to CD8(+) (P <0.05). Collectively, these findings indicate that the 4 polysaccharides possess significant immune-enhancing properties in chickens. This finding may have direct application in vaccine design and other strategies designed to potentiate immune system development and function in chickens.
Catechin stimulates osteogenesis by enhancing PP2A activity in human mesenchymal stem cells.
Using human mesenchymal stem cells, we identified catechin from a panel of herbal ingredients and Chinese traditional compounds with the strongest osteogenic effects. Catechin increased alkaline phosphatase activity, calcium deposition, and mRNA expression of Runx2 and osteocalcin. We further clarified the signaling pathway that catechin mediated to stimulate osteogenesis.