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Immunomodulatory Effect Goel et al studied the immunomodulatory effects of preparations of Echinacea containing cichoric acid, polysaccharides and alkylamides at different concentrations on male Sprague-Dawley rats. They found that Echinacea preparations are effective in stimulating an in vivo, non-specific immune response, such as increased release of cytokines, only when cichoric acid, polysaccharides and alkylamides at certain concentrations. [Echinacea stimulates macrophage function in the lung and spleen of normal rats.

Goel et al, University of Alberta, Canada. J Nutr Biochem. 2002 Aug;13(8):487.

O’Neill et al also concluded that Echinacea effectively stimulates immunocompetence, and the Echinacea extract improves the quality of blood by increasing hemaoglobin levels and the number of erthrocytes from their studies on eight horses. Immunological and hematinic consequences of feeding a standardized Echinacea extract to healthy horses.

O’Neill et al, Equine Research Centre, Canada, Equine Vet J. 2002 May;34(3):222-7

Common colds are one of the most frequent acute illnesses and Echinacea purpurea herb has shown promising results in the relief of common cold symptoms and shortening the duration for improvement. A randomized, double-blind, placebo-controlled clinical trial of 80 adult patients with first signs of a cold has shown that echinacea supplement was effective in alleviating symptoms more rapidly than placebo. The researchers also observed that echinacea supplements were well- tolerated in the study. Furthermore, a few more studies also concluded that Echinacea effectively reduced the symptoms and duration of the common cold. Echinacea appeared to be safe and no serious side effects were shown up in these studies.However, Yale et al. failed to replicate such benefits using 100 mg of freeze-dried pressed juice from the aerial portion of the echinacea purpurea. Turner RB et al also failed to replicate the findings in experimental rhinovirus infections. In the study, Turner utilized three doses of about 300 milligrams of the dried powdered echinacea root. The American Botanical Council (ABC), has pointed out that: {1} the extracts used were made in a university laboratory are different to commercial echinacea products. (2), the dosages used in this trial were also too low. According to ABC, various international monographs have acknowledged the generally higher dose used for echinacea root products. The World Health Organization (WHO) monograph for Echinacea root (“Radix Echinacea”) has a dosage for Echinacea agustifolia root at the equivalence of 3 gm per day of the dried root. This same dosage is also acknowledged in the more recently developed draft monographs on Echinacea from the Canadian Natural Health Products Directorate. This dosage level is about 330% higher than the dosage of the echinacea preparations given in the Turner’s trial.

Echinacea Agustifolia root - Echinacea species are perennials that belong to the Asteraceae (aster) family and originated in eastern North America. Traditionally used for a range of infections and cancers, the roots and herb (aboveground parts) of Echinacea species have attracted scientific interest for their reported use in enhancing the immune system.

Natural medicine experts frequently recommend oral extracts of echinacea for the treatment of the common cold and for other conditions requiring immune stimulation. It is occasionally recommended for topical treatment of wounds. Echinacea Angustifolia has been known to have many benefits and has been used for multiple medicinal purposes throughout the years. Some of its properties are antibacterial, anti putrefactive, anti inflammatory, antiviral, deodorant, diaphoretic, and aromatic and stimulating. This has been in human use for a very long time. It is a very good immune system stimulator as well and this is why the herb has been used to cure insect bites and stings as its application makes the area of the bite or sting numb and relieves it from pain. It even disinfects the area as well. In addition, Echinacea Agustifolia has also been used as an excellent remedy for tonsillitis, painful gums, sinusitis, lungs and digestive tract disorder. Its application also helps to fight off boils, septicemia, syphilis and many other blood impurities due to its antiseptic properties.

Traditionally, echinacea roots and herbs were used by indigenous Americans for a wide variety of conditions, ranging from snakebites to cancers. Echinacea does not have U.S. Food and Drug Administration (FDA) Generally Regarded as Safe (GRAS) status. Echinacea Agustifolia has evolved as an excellent multipurpose, naturally occurring antibody and is being used to cure many diseases. There are many scientific studies that have been done, and still others that are still being done, that have reported on the wide uses of this root. Echinacea Agustifolia root is well known to stimulate and strengthen the immune system. It is also used in today’s modern world as an excellent antibiotic and antiseptic, besides also fighting off inflammation and blood impurities. In addition Echinacea Agustifolia is quite useful for treating arthritis and rheumatism, staving off Colds, pneumonia and flu like symptoms and strengthens the body by strengthening its cells. It is an excellent remedy for different kinds of blood conditions and as well as a septic. Commonly used for tumors, cancers and abscesses and also for severe prostate conditions. Echinacea Agustifolia is also helpful for curing urinary tract infections.

Echinacea was adopted by central U.S. settlers in the 1800s. However, after the introduction of antibiotics, echinacea use fell out of favor. Echinacea’s historical use as a treatment for infections has found renewed interest due to recent rises in antibiotic resistance and the limitations of available antiviral drugs.

Echinacea Purpurea root, leaf, Echinacea should be of particular interest during the cold and flu season when you are exposed to these illnesses on a regular basis. When used correctly it is the closest thing to a cure for the common cold.

Echinacea stimulates the overall activity of the cells responsible for fighting all kinds of infection. Unlike antibiotics, which directly attack bacteria, echinacea makes our own immune cells more efficient at attacking bacteria, viruses and abnormal cells, including cancer cells. It increases the number and activity of immune system cells including anti-tumor cells, promotes T-cell activation, stimulates new tissue growth for wound healing and reduces inflammation in arthritis and inflammatory skin conditions.

The most consistently proven effect of echinacea is in stimulating phagocytosis (the consumption of invading organisms by white blood cells and lymphocytes). Extracts of echinacea can increase phagocytosis by 20-40%.

Echinacea also stimulates the production of interferon as well as other important products of the immune system, including “Tumor Necrosis Factor”, which is important to the body’s response against cancer.

Echinacea also inhibits an enzyme (hyaluronidase) secreted by bacteria to help them gain access to healthy cells. Research in the early 1950′s showed that echinacea could completely counteract the effect of this enzyme, helping to prevent infection when used to treat wounds. Although echinacea is usually used internally for the treatment of viruses and bacteria, it is now being used more and more for the treatment of external wounds. It also kills yeast and slows or stops the growth of bacteria and helps to stimulate the growth of new tissue. It combats inflammation too, further supporting its use in the treatment of wounds.
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